2. Signaling Pathways
  3. Membrane Transporter/Ion Channel
    Neuronal Signaling
  4. Calcium Channel
  5. P/Q-type calcium channel Isoform
  6. P/Q-type calcium channel Agonist

P/Q-type calcium channel Agonist

P/Q-type calcium channel Agonist (1):

Cat. No. Product Name Effect Purity
  • HY-12498
    GV-58
    		Agonist 99.22%
    GV-58 is a novel N- and P/Q-type calcium (Ca2+) channel agonist with EC50s of 7.21 and 8.81 μM, respectively. GV-58 slows the deactivation of channels, resulting in a large increase in presynaptic Ca2+ entry during activity. GV-58 can be used in lambert-eaton myasthenic syndrome (LEMS) research.